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ODN 24987
$450 – $2,350
Products Details
Product Description
– ODN 24987 is a Guanine-modified inhibitory oligonucleotides (ODN), targeting TLR9. ODN 24987 can inhibit IL-6 and IFN-α release. ODN 24987 can be used for research immune disorders. ODN 24987 sequence: 5’-C-C-T-G-G-C-c7G-G-G-G-3’[1].
Web ID
– HY-150745
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Römmler F, et al. Guanine modification of inhibitory oligonucleotides potentiates their suppressive function. J Immunol. 2013 Sep 15;191(6):3240-53.|[2]Römmler F, et al. Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells. PLoS One. 2015 Feb 19;10(2):e0116703.
CAS Number
– 1682661-48-8
Molecular Weight
– 3229.60
Compound Purity
– 92.42
SMILES
– [DNA, d(P-thio)(C-C-T-G-G-C-c7G-G-G-G)]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– H2O : ≥ 20 mg/mL
Target
– Toll-like Receptor (TLR)
Isoform
– TLR9
Pathway
– Immunology/Inflammation
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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