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ODN 1018
$420 – $1,450
Products Details
Product Description
– ODN 1018 (1018 ISS), an oligodeoxynucleotide, is a TLR-9 agonist. ODN 1018 is also a synthetic immunostimulatory sequence that can be used as vaccine adjuvant. Sequence: 5′-TGACTGTGAACGTTCGAGATGA-3′[1][2].
Web ID
– HY-150724
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– N/A
References
– [1]Friedberg JW, et al. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. Br J Haematol. 2009 Aug;146(3):282-91.|[2]Eng NF, et al. The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAVâ„¢ review. Hum Vaccin Immunother. 2013 Aug;9(8):1661-72.
CAS Number
– 937402-51-2
Molecular Weight
– 7150.00
Compound Purity
– 97.44
SMILES
– [DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A)]
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– H2O : ≥ 100 mg/mL
Target
– Toll-like Receptor (TLR)
Isoform
– TLR9
Pathway
– Immunology/Inflammation
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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