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Nω-Propyl-L-arginine (hydrochloride)
$120 – $620
Products Details
Product Description
– Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine hydrochloride displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2].
Web ID
– HY-102062A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C9H21ClN4O2
References
– [1]Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40(24):3869-70.|[2]Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503(1-3):103-7.
CAS Number
– 2321366-46-3
Molecular Weight
– 252.74
Compound Purity
– 98.0
SMILES
– N[C@@H](CCCNC(NCCC)=N)C(O)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 25 mg/mL (ultrasonic;warming)|DMSO : 25 mg/mL (ultrasonic;warming)
Target
– NO Synthase
Isoform
– nNOS
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
