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Products Details
Product Description
– Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O[1][2].
Web ID
– HY-115750
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C9H18N4O2
References
– [1]Zhang HQ, et, al. Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by Nω-Allyl-l-Arginine. J. Am. Chem. Soc. 1997, 119, 45, 10888-10902.|[2]Hah JM, et, al. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. Bioorg Med Chem. 2000 Aug;8(8):1931-6.
CAS Number
– 139461-37-3
Molecular Weight
– 214.26
SMILES
– N[C@@H](CCCNC(NCC=C)=N)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– NO Synthase
Isoform
– nNOS
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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