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NX-5948
$460 – $3,240
Products Details
Product Description
– NX-5948 (compound 195) is a potent BTK inhibitor via a ubiquitin proteolytic pathway[1].
Web ID
– HY-153321
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C42H54N12O5
References
– [1]Sands, et al. Bifunctional compounds for degrading btk via ubiquitin proteosome pathway. World Intellectual Property Organization, WO2021113557 A1. 2021-06-10.
CAS Number
– 2649400-34-8
Molecular Weight
– 806.96
Compound Purity
– 99.33
SMILES
– NC(C1=C(N=C(N2C[C@H](N3C(N(CC3)C)=O)CCC2)C=N1)NC4=CC=C(C5CCN(CC5)CC6CCN(C7=CN=C(C(N[C@@H]8C(NC(CC8)=O)=O)=O)C=C7)CC6)C=C4)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
