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Nusinersen
$700 – $2,700
Products Details
Product Description
– Nusinersen is an antisense oligonucleotide agent that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein[1].
Web ID
– HY-112980
Storage Temperature
– -20°C (Powder, stored under nitrogen, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-anti-virus
Molecular Formula
– C234H340N61O128P17S17
References
– [1]Richard S Finkel, et al. Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy. N Engl J Med. 2017 Nov 2;377(18):1723-1732.|[2]Laura Torres-Benito, et al. NCALD Antisense Oligonucleotide Therapy in Addition to Nusinersen further Ameliorates Spinal Muscular Atrophy in Mice. Am J Hum Genet. 2019 Jul 3;105(1):221-230.
CAS Number
– 1258984-36-9
Molecular Weight
– 7127.30
Compound Purity
– 99.62
SMILES
– [Nusinersen]
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in H2O
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
