NSC639828

$400$3,500

Products Details

Product Description

– NSC639828 is a potent inhibitor of DNA polymerase α with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease[1].

Web ID

– HY-145330

Storage Temperature

– -20°C (Powder, protect from light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C18H13BrClN5O3

References

– [1]Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428.

CAS Number

– 134742-26-0

Molecular Weight

– 462.68

Compound Purity

– 99.91

SMILES

– O=C(NC1=CC=C(C(Cl)=C1)OC2=NC=C(C=N2)Br)NC(C3=C(N)C=CC=C3)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– DNA/RNA Synthesis

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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