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NSC622608
SKU
HY-147311-10 mg
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, PD-1/PD-L1
$110 – $570
Products Details
Product Description
– NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 μM[1].
Web ID
– HY-147311
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C9H12BrN3OS2
References
– [1]Gabr MT, et al. Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA). J Am Chem Soc. 2020 Sep 23;142(38):16194-16198.
CAS Number
– 2593254-90-9
Molecular Weight
– 322.25
Compound Purity
– 99.53
SMILES
– CN(C)C1=N/C(SS1)=N/CC2=CC=CO2.Br
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 12.5 mg/mL (ultrasonic)
Target
– PD-1/PD-L1
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.