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Products Details
Product Description
– NSC381467 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC381467 has strong antiproliferative activities. NSC381467 has the potential for the research of cancer diseases[1].
Web ID
– HY-144444
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H16O7
References
– [1]Jiwacharoenchai N, et al. Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation. Bioorg Med Chem Lett. 2022;58:128524.
CAS Number
– 1033006-96-0
Molecular Weight
– 368.34
SMILES
– COC1=CC=CC2=C1C(C3=C(C4=C([C@H]([C@@H]3O)O)C=C(C=C4O)CO)C2=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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