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Products Details
Product Description
– NSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases[1].
Web ID
– HY-144445
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H20O4
References
– [1]Jiwacharoenchai N, et al. Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation. Bioorg Med Chem Lett. 2022;58:128524.
CAS Number
– 24909-18-0
Molecular Weight
– 348.39
SMILES
– O=C1C(C2=CC=C(CC)C=C2)=C(O)C(C(C3=CC=C(CC)C=C3)=C1O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
