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Products Details
Product Description
– NSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase[1][2].
Web ID
– HY-130369
Shipping
– Room temperature
Molecular Formula
– C31H42Cl2N4O2
References
– [1]Amritansh Bhanot, et al. Discovery of small molecule inhibitors of Mycobacterium tuberculosis ClpC1: SAR studies and antimycobacterial evaluation. Results in Chemistry. Volume 5, January 2023, 100904.|[2]Dzeng RK, et al. Small molecule growth inhibitors of human oncogenic gammaherpesvirus infected B-cells. Mol Oncol. 2015 Feb;9(2):365-76.
CAS Number
– 6286-09-5
Molecular Weight
– 573.60
SMILES
– CC1=NC2=CC=C(OC)C=C2C(NCCCCCCCCCNC3=CC(C)=NC4=CC=C(OC)C=C34)=C1.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;HSV;Necroptosis
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
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