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Products Details
Product Description
– NSC 828467 exhibited significant in vitro anticancer activity,and it is one of the top-five CA IX inhibitors with an IC50 value of 27.2nM.
Web ID
– HY-144222
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H19N9O2S
References
– [1]Tawfik HO, et al. Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach. Eur J Med Chem. 2022 Feb 12;232:114190.
Molecular Weight
– 461.50
SMILES
– NS(=O)(C1=CC=C(C=C1)NC2=NC(N/N=C/C3=NC=CC=C3)=NC(NC4=CC=CC=C4)=N2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
