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NSC 828467
SKU
HY-144222-Get quote
Category Reference compound
Tags Cancer, Carbonic Anhydrase, Metabolic Enzyme/Protease
Products Details
Product Description
– NSC 828467 exhibited significant in vitro anticancer activity,and it is one of the top-five CA IX inhibitors with an IC50 value of 27.2nM.
Web ID
– HY-144222
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H19N9O2S
References
– [1]Tawfik HO, et al. Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach. Eur J Med Chem. 2022 Feb 12;232:114190.
Molecular Weight
– 461.50
SMILES
– NS(=O)(C1=CC=C(C=C1)NC2=NC(N/N=C/C3=NC=CC=C3)=NC(NC4=CC=CC=C4)=N2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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