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Products Details
Product Description
– NSC 288387 is a pan-flavivirus MTase inhibitor. NSC 288387 binds to the SAM-binding pocket. NSC 288387 inhibits ZIKV with an IC50 of 0.2 μM. NSC 288387 also inhibits viral replication in cell culture[1].
Web ID
– HY-134309
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C19H16N4O3
References
– [1]Samrat SK, et al. Broad-Spectrum Small-Molecule Inhibitors Targeting the SAM-Binding Site of Flavivirus NS5 Methyltransferase. ACS Infect Dis. 2023 Jul 14;9(7):1319-1333.
CAS Number
– 61369-43-5
Molecular Weight
– 348.36
SMILES
– O=C(N1C2=CC=CC=C2)N=C3N(CCOC)C4=CC=CC=C4N=C3C1=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Virus Protease
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
