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NSC-207895
$150 – $1,280
Products Details
Product Description
– NSC-207895 (XI-006), a DNA damaging agent, is an anticancer agent and p53 activator[1][2][3].
Web ID
– HY-14714
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H13N5O4
References
– [1]Laura Kapitzky, et al. Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol. 2010 Dec 21;6:451.|[2]Erdenezaya Odkhuu, et al. Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B. Immunobiology. 2015 Jan;220(1):136-41.|[3]Luis A Carvajal, et al. Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia. Sci Transl Med. 2018 Apr 11;10(436):eaao3003.
CAS Number
– 58131-57-0
Molecular Weight
– 279.25
Compound Purity
– 98.97
SMILES
– O=[N+](C1=CC=C(N2CCN(C)CC2)C3=[N+]([O-])ON=C31)[O-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
