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NSC 185058
$109 – $370
Products Details
Product Description
– NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity[1].
Web ID
– HY-125169
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C11H9N3S
References
– [1]Huang T, et al. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 2017 Dec 11;32(6):840-855.e8.
CAS Number
– 39122-38-8
Molecular Weight
– 215.27
Compound Purity
– 99.52
SMILES
– S=C(C1=NC=CC=C1)NC2=NC=CC=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 125 mg/mL
Target
– Atg4;Autophagy
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
