Download Files:
NS 9283
$120 – $920
Products Details
Product Description
– NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD), schizophrenia, Parkinson’s disease and Alzheimer’s disease[1].
Web ID
– HY-110168
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C14H8N4O
References
– [1]M Grupe, et al. Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)<sub>3</sub>(β2) <sub>2</sub>nicotinic ACh receptors. Br J Pharmacol. 2013 Apr;168(8):2000-10.
CAS Number
– 913830-15-6
Molecular Weight
– 248.24
Compound Purity
– 98.36
SMILES
– N#CC1=CC=CC(C2=NC(C3=CN=CC=C3)=NO2)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
