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Products Details
Product Description
– Nrf2/HO-1 activator 1 (Compound 24) is a potent Nrf2/HO-1 activator, neuroprotective agent. Nrf2/HO-1 activator 1 shows neuroprotective and antioxidant activities. Nrf2/HO-1 activator 1 can be used in Parkinson’s disease (PD) research[1].
Web ID
– HY-151430
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C21H18O5
References
– [1]Qili Lu, et al. Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson’s disease via the activation of Nrf2/HO-1 signaling. Eur J Med Chem. 2022 Nov 15;242:114692.
CAS Number
– 2883506-60-1
Molecular Weight
– 350.36
SMILES
– O=C1C(C2=CC=C(OC)C=C2)=COC3=C1C4=C(C=CC(C)(C)O4)C(O)=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Akt;ERK;JNK;Keap1-Nrf2;Reactive Oxygen Species
Pathway
– Immunology/Inflammation;MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
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