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Products Details
Product Description
– Nrf2 activator-5 (compound 1) is a potent Nrf2 activator that can attenuate H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglial cells. Nrf2 activator-5 exhibits antioxidant and anti-inflammatory activities[1].
Web ID
– HY-146168
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H30Cl2O6
References
– [1]Choi JW, et, al. Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities. Bioorg Chem. 2020 Dec;105:104434.
CAS Number
– 1012860-13-7
Molecular Weight
– 497.41
SMILES
– O=C([C@]1(Cl)[C@@]2(C/C=C(C)/CC/C=C(C)/CO)OC(C)(C)[C@H](Cl)C1)C3=C(C2=O)C=C(O)C=C3O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Keap1-Nrf2
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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