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NPB
$280 – $2,280
Products Details
Product Description
– NPB is a specific and potent inhibitor of BAD phosphorylation at Ser99, with an IC50 of 0.41 μM[1].
Web ID
– HY-119368
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H31Cl2N3O2
References
– [1]Pandey V, et al. Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10505-E10514.
CAS Number
– 2247491-97-8
Molecular Weight
– 524.48
Compound Purity
– 98.0
SMILES
– OC1=C(C(N2CCN(C3=C(Cl)C(Cl)=CC=C3)CC2)C4=CC=CC(C(NC5CCCC5)=O)=C4)C=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
