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NP-313

$150$770

Products Details

Product Description

– NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca2+ inward flow[1].

Web ID

– HY-129496

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Molecular Formula

– C12H8ClNO3

References

– [1]Heng-Lan Kuo, et al. NP-313, 2-acetylamino-3-chloro-1,4-naphthoquinone, a novel antithrombotic agent with dual inhibition of thromboxane A(2) synthesis and calcium entry. Br J Pharmacol. 2011 Apr;162(8):1871-83. 

CAS Number

– 5397-78-4

Molecular Weight

– 249.65

Compound Purity

– 99.58

SMILES

– CC(NC(C1=O)=C(Cl)C(C2=C1C=CC=C2)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– DMSO : 25 mg/mL (ultrasonic)

Target

– Thrombin

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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