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NOS-IN-3

Products Details

Product Description

– NOS-IN-3 (Compound 9a) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 4.6 μM, without inhibiting eNOS. NOS-IN-3 has little toxicity and can be studied in the research of inducible isoform involved diseases, such as septic shock[1].

Web ID

– HY-115917

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C10H15N3O

References

– [1]Fabio Arias, et al. Bioactive imidamide-based compounds targeted against nitric oxide synthase. Bioorg Chem. 2022 Feb 2;120:105637.

CAS Number

– 2761725-68-0

Molecular Weight

– 193.25

SMILES

– CC(NCCC(C1=CC=CN=C1)O)=N

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– NO Synthase

Isoform

– iNOS;nNOS

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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