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Norepinephrine (tartrate)
Products Details
Product Description
– Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors[1][2][3][4].
Web ID
– HY-13715C
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C12H17NO9
References
– [1]MacGregor DA, et al. Relative efficacy and potency of beta-adrenoceptor agonists for generating cAMP in human lymphocytes. Chest. 1996 Jan;109(1):194-200.|[2]Littlejohn NK, et al. Suppression of Resting Metabolism by the Angiotensin AT2 Receptor. Cell Rep. 2016 Aug 9;16(6):1548-60.|[3]Brian P Ramos, et al. Adrenergic pharmacology and cognition: focus on the prefrontal cortex. Pharmacol Ther. 2007 Mar;113(3):523-36.|[4]Xinyu Xu, et al. Binding pathway determines norepinephrine selectivity for the human β 1 AR over β 2 AR. Cell Res. 2021 May;31(5):569-579.
CAS Number
– 51-40-1
Molecular Weight
– 319.26
SMILES
– OC1=CC=C([C@@H](O)CN)C=C1O.OC([C@H](O)[C@@H](O)C(O)=O)=O
Clinical Information
– Launched
Research Area
– Endocrinology; Cardiovascular Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;Autophagy;Endogenous Metabolite
Isoform
– Human Endogenous Metabolite;Microbial Metabolite;α adrenergic receptor;β adrenergic receptor
Pathway
– Autophagy;GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Natural Products
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