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Nocloprost
$389
Only 1000 item(s) left in stock.
Products Details
Product Description
– Nocloprost, a prostaglandin E2 (PGE2) analog, is an orally active EP1- and EP3-receptor agonist. Nocloprost inhibits evoked [3H]ACh release. Nocloprost has gastroprotective and ulcer-healing properties. Nocloprost accelerates the healing of chronic gastric ulcerations and enhances mucosal growth in rats[1][2].
Web ID
– HY-106054
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C22H37ClO4
References
– [1]S J Konturek, et al. Nocloprost, a unique prostaglandin E2 analog with local gastroprotective and ulcer-healing activity. Eur J Pharmacol. 1991 Apr 3;195(3):347-57.|[2]T Reinheimer, et al. Prostanoid receptors of the EP3 subtype mediate inhibition of evoked [3H]acetylcholine release from isolated human bronchi. Br J Pharmacol. 1998 Sep;125(2):271-6.
CAS Number
– 79360-43-3
Molecular Weight
– 400.98
SMILES
– CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H]([C@H](Cl)C[C@H]1O)C/C=CCCCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
