Download Files:
NMS-873
$78 – $782
Products Details
Product Description
– NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with an IC50 value of 30 nM.
Web ID
– HY-15713
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H28N4O3S2
References
– [1]Paola Magnaghi, et al. Covalent and allosteric inhibitors of the ATPATP ase VCP/p97 induce cancer cell death. Nat Chem Biol. 2013 Jul 28. doi: 10.1038/nchembio.1313.
CAS Number
– 1418013-75-8
Molecular Weight
– 520.67
Compound Purity
– 99.87
SMILES
– CC(C=C(OCC1=NN=C(SC2CCCC2)N1C3=CC=CN=C3)C=C4)=C4C5=CC=C(S(=O)(C)=O)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 20.5 mg/mL (ultrasonic;warming)
Target
– p97
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
