NMI 8739

$71$1,680

Products Details

Product Description

– NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.

Web ID

– HY-101540

Storage Temperature

– -20°C (Powder, protect from light)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C30H41NO3

References

– [1]Wang Y, et al. N-Docosahexaenoyl Dopamine, an Endocannabinoid-like Conjugate of Dopamine and the n-3 Fatty Acid Docosahexaenoic Acid, Attenuates Lipopolysaccharide-Induced Activation of Microglia and Macrophages via COX-2. ACS Chem Neurosci. 2017 Mar 15;8(3):548-557.|[2]Gill Higgins, New drugs signal rapid growth of anti-obesity drug market. RESEARCH & DEVELOPMENT. 2 Nov 11K16 No. 1061|[3]Shashoua VE, et al. N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite. Life Sci. 1996;58(16):1347-57.

CAS Number

– 129024-87-9

Molecular Weight

– 463.65

Compound Purity

– 99.02

SMILES

– CC/C=CC/C=CC/C=CC/C=CC/C=CC/C=CCCC(NCCC1=CC=C(O)C(O)=C1)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 65 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)

Target

– Dopamine Receptor

Isoform

– D2 Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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