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Products Details
Product Description
– NMDA receptor antagonist 6 (compound 13b) is an antagonist of NMDA receptor, targeting to the glycine binding site. NMDA receptor antagonist 6 shows cytoneuroprotective potency, and protects PC12 cells against NMDA-induced injury and cell apoptosis[1].
Web ID
– HY-155049
Shipping
– Room temperature
Molecular Formula
– C25H23NO2
References
– [1]Yang L, et al. Design, synthesis and evaluation of novel 1-phenyl-pyrrolo [1, 2-b] isoquinolin-3-one derivatives as antagonists for the glycine binding site of the NMDA receptor[J]. European Journal of Medicinal Chemistry, 2023: 115624.
Molecular Weight
– 369.46
SMILES
– O=C1N2CC3=CC=CC=C3CC2C(C4=CC(OCC5=CC=CC=C5)=CC=C4)C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
