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Products Details
Product Description
– NMDA receptor antagonist 4 (IIc) is a uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC50 of 1.93 µM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability, and can be studied in Alzheimer’s disease[1].
Web ID
– HY-146588
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C15H18FN
References
– [1]Andreea L. Turcu, et al. Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer’s disease. Eur J Med Chem. 2022 Apr 8;236:114354.
CAS Number
– 1607589-56-9
Molecular Weight
– 231.31
SMILES
– NC12CC3C4=CC=CC=C4C(CC(F)(C2)C3)C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
