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Products Details
Product Description
– NLRP3-IN-24 (Compounds 15a) is an inhibitor against NLRP3. NLRP3-IN-24 has an inhibitory effect on the activation of NLRP3 inflammasome[1].
Web ID
– HY-157147
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H26O3Si
References
– [1]Shete S S, et al. Sila-CBD Derivatives as Inhibitors of Heme-Induced NLRP3 Inflammasome: Application in Hemolytic Diseases[J]. ACS Medicinal Chemistry Letters, 2023.
Molecular Weight
– 330.49
SMILES
– O=C(C=C1[Si](C)(C)C)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Interleukin Related;TNF Receptor
Isoform
– IL-1;IL-6
Pathway
– Apoptosis;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
