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Products Details
Product Description
– NLRP3-IN-23 (Compound 15C) is an inhibitor of heme-mediated induction of the NLRP3 inflammasome. NLRP3-IN-23 significantly inhibits heme-mediated induction of the NLRP3 inflammasome at a concentration of 0.1 μM[1].
Web ID
– HY-157146
Shipping
– Room temperature
Molecular Formula
– C24H36O3Si
References
– [1]Shete S S, et al. Sila-CBD Derivatives as Inhibitors of Heme-Induced NLRP3 Inflammasome: Application in Hemolytic Diseases[J]. ACS Medicinal Chemistry Letters, 2023.
Molecular Weight
– 400.63
SMILES
– O=C(C=C1[Si](C)(CCCCCC)C)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NOD-like Receptor (NLR)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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