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NLRP3-IN-11
$150 – $1,350
Products Details
Product Description
– NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].
Web ID
– HY-148187
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H17ClN4O2
References
– [1] HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.
CAS Number
– 2769040-91-5
Molecular Weight
– 344.80
Compound Purity
– 98.79
SMILES
– ClC1=CC=C(C2=C3C=CN=CC3=C(NCC(C)(C)O)N=N2)C(O)=C1
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– NOD-like Receptor (NLR)
Isoform
– NLRP3
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
