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Products Details
Product Description
– NLRP3 antagonist 1 is a potent antagonist of NLRP3. NLRP3 is mainly expressed in macrophages and neutrophils and is involved in the body’s intrinsic immunity against pathogenic infections and stress injury. NLRP3 antagonist 1 has the potential for the research of cancer disease (extracted from patent WO2021114691A1, compound 3)[1].
Web ID
– HY-143563
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H18N6O
References
– [1]Zejin You, et al. Nitrogen-containing and cyclic compounds, their preparation methods and uses. Patent WO2021114691A1.
CAS Number
– 2454017-83-3
Molecular Weight
– 310.35
SMILES
– O[C@@H]1[C@H](NC2=C3C=CC(C4=NNC=C4)=CC3=NC(N)=N2)CCC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NOD-like Receptor (NLR)
Isoform
– NLRP3
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
