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Products Details
Product Description
– NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model[1].
Web ID
– HY-149358
Shipping
– Room temperature
Molecular Formula
– C17H16FN5OS
References
– [1]Ye L, et al. Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor. Eur J Med Chem. 2023 Sep 5;257:115486.
CAS Number
– 2854331-14-7
Molecular Weight
– 357.41
SMILES
– FC1=CC=C(C(N2CCN3C([C@H]2C)=CN=C3C4=NC(C)=NS4)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Neurokinin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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