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NJH-2-030
$400 – $3,400
Products Details
Product Description
– NJH-2-030 can be used as a covalent recruiter for FEM1B in targeted protein degradation applications. NJH-2-030 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-143348
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H20ClN3O3
References
– [1]Henning NJ, et al. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. J Am Chem Soc. 2022 Jan 19;144(2):701-708.
CAS Number
– 2709040-02-6
Molecular Weight
– 373.83
Compound Purity
– 98.74
SMILES
– C#CCCCC(N1CCOC2=C1C=CC(N(C(CCl)=O)CCC#N)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– E3 Ligase Ligand-Linker Conjugates
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
