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Products Details
Product Description
– Nizubaglustat is an inhibitor of Ceramide Glucosyltransferase or Glucosylceramide Synthase (GCS). Nizubaglustat also inhibits GBA2, involving in neuropathological lysosomal storage disorders[1][2].
Web ID
– HY-148786
Shipping
– Room temperature
Molecular Formula
– C24H32FNO5
References
– [1]Ghisaidoobe AT, et al. Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. J Med Chem. 2014 Nov 13;57(21):9096-104.|[2]WHO Drug Information-World Health Organization (WHO).
CAS Number
– 1633666-49-5
Molecular Weight
– 433.51
SMILES
– FC1=C(C2=CC=CC=C2)C=CC(COCCCCCN3[C@H]([C@H]([C@@H]([C@H](C3)O)O)O)CO)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Glucosylceramide Synthase (GCS)
Pathway
– Neuronal Signaling
Product type
– Reference compound
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