Nicotinamide N-oxide

$60$66

Products Details

Product Description

– Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.

Web ID

– HY-101407

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C6H6N2O2

References

– [1]Real AM, et al. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes. Drug Metab Dispos. 2013 Mar;41(3):550-3.|[2]Cutshall NS, et al. Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1951-4.

CAS Number

– 1986-81-8

Molecular Weight

– 138.12

Compound Purity

– 99.85

SMILES

– O=C(C1=C[N+]([O-])=CC=C1)N

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Endocrinology

Solubility

– DMSO : 10 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)

Target

– CXCR;Drug Metabolite;Endogenous Metabolite

Isoform

– CXCR2

Pathway

– GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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