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Nicotinamide N-oxide
SKU
HY-101407-100 mg
Category Natural Products
Tags CXCR;Drug Metabolite;Endogenous Metabolite, GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease, Inflammation/Immunology; Endocrinology
$60 – $66
Products Details
Product Description
– Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.
Web ID
– HY-101407
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C6H6N2O2
References
– [1]Real AM, et al. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes. Drug Metab Dispos. 2013 Mar;41(3):550-3.|[2]Cutshall NS, et al. Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1951-4.
CAS Number
– 1986-81-8
Molecular Weight
– 138.12
Compound Purity
– 99.85
SMILES
– O=C(C1=C[N+]([O-])=CC=C1)N
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Endocrinology
Solubility
– DMSO : 10 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)
Target
– CXCR;Drug Metabolite;Endogenous Metabolite
Isoform
– CXCR2
Pathway
– GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.