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Nicodicosapent
$120 – $1,800
Products Details
Product Description
– Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.
Web ID
– HY-17640
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C28H39N3O2
References
– [1]Vu CB, et al. Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid. J Med Chem. 2016 Feb 11;59(3):1217-31.
CAS Number
– 1269181-69-2
Molecular Weight
– 449.63
Compound Purity
– 98.04
SMILES
– O=C(C1=CC=CN=C1)NCCNC(CCC/C=CC/C=CC/C=CC/C=CC/C=CCC)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : ≥ 100 mg/mL|Ethanol : 3.33 mg/mL (ultrasonic)
Target
– Autophagy;Fatty Acid Synthase (FASN)
Pathway
– Autophagy;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
