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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (hydrochloride)
$424 – $3,278
Products Details
Product Description
– NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) hydrochloride is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].
Web ID
– HY-148819A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Molecular Formula
– C26H24ClN3O6
References
– [1]Andrew C. Phillips, et al. Anti-c-met antibody drug conjugates.WO2022232834.
Molecular Weight
– 509.94
Compound Purity
– 95.10
SMILES
– NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– ADC Cytotoxin;Topoisomerase
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
