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Products Details
Product Description
– NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].
Web ID
– HY-148819
Shipping
– Room temperature
Molecular Formula
– C26H23N3O6
References
– [1]Andrew C. Phillips, et al. Anti-c-met antibody drug conjugates.WO2022232834.
CAS Number
– 2857037-69-3
Molecular Weight
– 473.48
SMILES
– NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;Topoisomerase
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
