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Products Details
Product Description
– NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].
Web ID
– HY-108659
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C37H26N4Na4O15S4
References
– [1]Feng Gao, et al. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis. IUBMB Life. 2019 Oct;71(10):1552-1560.
CAS Number
– 202982-98-7
Molecular Weight
– 986.84
SMILES
– O=C(NC1=CC(C(NC2=C3C=C(S(=O)(O[Na])=O)C=CC3=CC(S(=O)(O[Na])=O)=C2)=O)=CC=C1C)NC4=CC(C(NC5=C6C=C(S(=O)(O[Na])=O)C=CC6=CC(S(=O)(O[Na])=O)=C5)=O)=CC=C4C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– P2Y Receptor
Isoform
– P2Y11 Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
