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Products Details
Product Description
– NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent through the mechanism of decreasing the protein expressions of iNOS and COX-2 by suppressing NF-κB signaling pathway. NF-κB-IN-6 inhibits NO production in LPS-induced RAW264.7 cells with an IC50 of 23.1 μM[1].
Web ID
– HY-147770
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H20N2O3
References
– [1]Li SM, et al. Bioactivity Study of Tricyclic and Tetracyclic Genipin Derivatives as Anti-inflammatory Agents. Bioorg Chem. 2022 Sep;126:105881.
Molecular Weight
– 264.32
SMILES
– [H][C@]12CC=C(CO)[C@@]1([H])C3N(C)CCN3C=C2C(OC)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
