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Products Details
Product Description
– NF-κB-IN-3 (Compound 2) is a NF-κB inhibitor with an IC50 of 0.70 µM. NF-κB-IN-3 can be used as an antitumor agent[1].
Web ID
– HY-144744
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H18ClF3N2O2
References
– [1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.
CAS Number
– 1873311-82-0
Molecular Weight
– 458.86
SMILES
– O=C(C1CCC2=CC=CC=C2N1C(C3=CC=CC(Cl)=C3)=O)NC4=CC=CC=C4C(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NF-κB
Isoform
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
