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Products Details
Product Description
– NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities[1].
Web ID
– HY-146058
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H16N6O4S2
References
– [1]Soliman AM, et al. Antioxidant activity of novel quinazolinones bearing sulfonamide: Potential radiomodulatory effects on liver tissues via NF-κB/ PON1 pathway. Eur J Med Chem. 2020 Jul 1;197:112333.
CAS Number
– 2419107-97-2
Molecular Weight
– 468.51
SMILES
– O=C(NC1=NC=CN=C1)CSC(N2C3=CC=C(S(=O)(N)=O)C=C3)=NC4=C(C=CC=C4)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NF-κB;Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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