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Products Details
Product Description
– NF-κB-IN-12 (compound 3h) is a potent NF-κB inhibitor, with an IC50 of 1.02 μM. NF-κB-IN-12 can be used for acute lung injury research[1].
Web ID
– HY-149580
Shipping
– Room temperature
Molecular Formula
– C30H26N6O5S
References
– [1]Zang B, et al. Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis. Acta Pharm. 2023 Sep 14;73(3):341-362.
Molecular Weight
– 582.63
SMILES
– O=C(N1N=CC(C2=CC=C(S(=O)(C3=CC=C(O)C=C3)=O)C=C2)C1C4=CC=C(OC)C=C4)C5=CN6C(C(NC)=NC=C6)=N5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
