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Nexopamil (racemate)
SKU
HY-101727-Get quote
Category Reference compound
Tags 5-HT Receptor;Calcium Channel, Cardiovascular Disease, GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Products Details
Product Description
– Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on thrombus formation in vivo and on platelet aggregation in vitro.
Web ID
– HY-101727
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H40N2O3
References
– [1]Kirchengast M, et al. Inhibition by the combined Ca2+ and 5-HT2 receptor antagonist nexopamil (LU 49938) of intracoronary thrombus formation in a canine model of arterial stenosis and intimal damage. J Cardiovasc Pharmacol. 1993 Nov;22(5):687-94.
CAS Number
– 116759-35-4
Molecular Weight
– 404.59
SMILES
– N#CC(C(C)C)(CCCN(CCCCCC)C)C1=CC(OC)=C(OC)C(OC)=C1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Calcium Channel
Isoform
– 5-HT2 Receptor;Calcium Channel
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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