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Products Details
Product Description
– Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. Nevadistinel can be used to inhibit cognitive impairment associated with neurodegenerative diseases, such as mild cognitive impairment, mild Alzheimer’s disease, Parkinson’s disease, Lewy body disease[1].
Web ID
– HY-156626
Shipping
– Room temperature
Molecular Formula
– C15H18N2O3
References
– [1]Khan, et al. Preparation of spiro-lactam as NMDA receptor modulators for the treatment of depression and related disorders. World Intellectual Property Organization, WO2018026798 A1. 2018-02-08.
CAS Number
– 2181816-92-0
Molecular Weight
– 274.32
SMILES
– O=C1[C@@]2(CC(NCC2)=O)CN1CC3=CC=C(C=C3)OC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
