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Products Details
Product Description
– Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (PR3) with IC50 values of 4.91 μM and 20.69 μM, respectively. Neutrophil elastase inhibitor 5 can be used in the study of neutrophil inflammatory diseases[1].
Web ID
– HY-155414
Shipping
– Room temperature
Molecular Formula
– C24H18N4O4
References
– [1]Hwang TL, et al. Design and synthesis of sirtinol analogs as human neutrophil elastase inhibitors. Bioorg Med Chem Lett. 2023 Nov 7;97:129544
Molecular Weight
– 426.42
SMILES
– OC([C@H](C1=CC=CC=C1)NC(C2=NC=CC=C2/N=N/C3=C(C=CC=C4)C4=CC=C3O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Elastase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
