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Products Details
Product Description
– Neuroinflammatory-IN-3, a tubulin inhibitor, is an anti-neuroinflammatory agent. Neuroinflammatory-IN-3 is a potent antitumor agent that functions by the inhibition of tubulin polymerization[1][2].
Web ID
– HY-152088
Shipping
– Room temperature
Molecular Formula
– C19H19ClO3
References
– [1]Junhyeong Yim, et al. Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin-p65 interaction. Exp Mol Med. 2022 Dec 12;1-10|[2]Jongmin Park, et al. Discovery and target identification of an antiproliferative agent in live cells using fluorescence difference in two-dimensional gel electrophoresis. Angew Chem Int Ed Engl. 2012 May 29;51(22):5447-51.
CAS Number
– 1202404-23-6
Molecular Weight
– 330.81
SMILES
– OC1=C(OC)C=CC2=C1OC(C)(C)C=C2C3=CC=C(Cl)C=C3C
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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