Neocryptotanshinone

$550$920

Products Details

Product Description

– Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways[1][2].

Web ID

– HY-119720

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C19H22O4

References

– [1]Chuanhong Wu, et al. Neocryptotanshinone Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages by Suppression of NF-κB and iNOS Signaling Pathways. Acta Pharm Sin B. 2015 Jul;5(4):323-9.|[2]H C Lin, et al. Two New Fatty Diterpenoids From Salvia Miltiorrhiza. J Nat Prod. 2001 May;64(5):648-50.|[3]FENG Jinghui, et al. Effects of Salvia miltiorrhiza Bunge extract and its single components on monosodium urate-induced pain in vivo and lipopolysaccharide-induced inflammation in vitro. J Tradit Chin Med. 2021. 41(2): 219-226.

CAS Number

– 109664-02-0

Molecular Weight

– 314.38

Compound Purity

– 98.82

SMILES

– O=C1C([C@@H](C)CO)=C(O)C(C2=C1C=CC3=C2CCCC3(C)C)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– NF-κB;NO Synthase

Isoform

– iNOS

Pathway

– Immunology/Inflammation;NF-κB

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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