Download Files:
Nelarabine
$106 – $697
Products Details
Product Description
– Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL)[1].
Web ID
– HY-13701
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H15N5O5
References
– [1]Lonetti A, et al. Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway. J Hematol Oncol. 2016 Oct 24;9(1):114.|[2]Wang H, et al. Repurposing Nelarabine to Induce Differentiation of Acute Myeloid Leukemia. Blood, 2020, 136: 26.
CAS Number
– 121032-29-9
Molecular Weight
– 297.27
Compound Purity
– 99.88
SMILES
– OC[C@@H]1[C@@H](O)[C@H](O)[C@H](N2C=NC3=C(OC)N=C(N)N=C23)O1
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
Target
– Apoptosis;Nucleoside Antimetabolite/Analog
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
