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Product Description
– Neladenoson dalanate (Neladenoson bialanate; BAY-1067197) hydrochloride is a orally active agonist precursor of partial Adenosine A1 Receptor. Neladenoson dalanate hydrochloride has a good pharmacokinetic and safety profile, can be used for the chronic heart diseases[1].
Web ID
– HY-115494
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C35H35Cl2N7O4S2
References
– [1]Meibom D, et al. Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A1 Receptor Agonist for the Chronic Treatment of Heart Diseases. ChemMedChem. 2017 May 22;12(10):728-737.
CAS Number
– 1239235-25-6
Molecular Weight
– 752.73
SMILES
– C[C@@H](C(OCCOC1=CC=C(C2=C(C#N)C(SCC3=CSC(C4=CC=C(Cl)C=C4)=N3)=NC(N5CCCC5)=C2C#N)C=C1)=O)NC([C@H](C)N)=O.[H]Cl
Clinical Information
– Phase 2
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adenosine Receptor
Isoform
– Adenosine A1 receptor (A1R)
Pathway
– GPCR/G Protein
Product type
– Reference compound
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